Abstract

Intravenous lipid emulsion (ILE) is a mixture of long chain fatty acids or medium chain fatty acids or a combination of both that was first formulated for intravenous administration to supply necessary fatty acids and a dense source of calories for patients on parenteral nutrition (PN). The available formulations contain alternative sources of fatty acids, such as medium-chain triglyceride oils, olive, fish, and soybean oils. Lipid emulsion as a rescue agent for intentional and inadvertent overdoses of liphophilic substances has created a new therapeutic window for the drugs that do not have any specific antidote in the market. The use of ILE therapy is nowadays used a new antidote for the treatment of toxicity of liphophilic pharmaceutical agents.

Keywords : Antidote, Emulsion, Liphophilic, Toxicity